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PURDUE    _,    ,
verermary medical
VOLUME 9, NUMBER 2
SUMMER- FALL 1983
A Message from the President
Steven C. Beering, M.D., Ninth President of Purdue University
Although I am still new to Purdue, I feel
like the School of Veterinary Medicine
and I are old friends. We first teamed up
in 1970 when I took responsibility for
Indiana's Statewide Medical Education
System. The Lafayette link in that much-
emulated program would not have been
possible without the Purdue veterinary
medical school's spirited participation.
Dean Jack Stockton, his faculty and students-true to the school's tradition of
excellent education and service-have
supplied that spirit from the beginning.
As Indiana's sole provider of veterinary
medical education and one of only 27
such schools in the country, the Purdue
veterinary medical school has a proud
past and an exciting present. But it has
awesome responsibilities for the future.
In an era when costs are rising faster than
the levels of public support, it will take
greater efforts by all of us iust to main
tain the excellence of the school's teaching and the quality of its graduates-and
that will not be enough.
To better meet the needs of the state and
the nation, we have to look to new challenges. For the veterinary medical school,
one of these challenges is to make our
research function as excellent and as
deeply respected as our educational programs. This will require long-term growth
in people, facilities and funding, and it
will take hard work, creativity and a willingness to serve by all of us.
The School of Veterinary Medicine, however, will not be alone in this endeavor.
My vision of Purdue's future is one of a
uniform excellence achieved and sustained through common effort. Every
individual, every program, every school at
Purdue has certain limitations, but together we can break those limits.   Our
university, as great as its past has been,
can have an even greater future. All of
us-students,   faculty,  staff,  alumni  and
friends-are part of the theme we have
adopted: Touching Tomorrow Today.
The theme is symbolized by the space
shuttle, Challenger, which carried Purdue
student experiments into space. Figuratively, we are all aboard that spaceship,
not just as passengers, but as the workers
of tomorrow's wonders.
Steven C Beering
President
Born in Berlin, Germany, in 1932, Steven Claus
Beering emigrated to the U.S. following World War II
and graduated from Taylor Allerdice High School in
Pittsburgh, Pa. Following earned B.S. and M.D. degrees from the University of Pittsburgh, he completed
an internship at the Walter Reed General Hospital and
a residency program in internal medicine at the Wil-
ford Hall USAF Medical Center, San Antonio, Texas,
where he remained on staff until joining the Indiana
University School of Medicine as assistant dean and
professor of medicine in 1969. He was appointed
dean of that school in 1974. He holds numerous appointments on boards, on committees, and in societies, and has published in his medical specialty area.
He came to Purdue officially on 1 July 1983, as the University's 9th president. The
School of Veterinary Medicine has known him well since 1970 when he directed
the Indiana Statewide Medical Education System in which this School has been a
participant from its inception.
In Vitro Animal Disease Modeling
Research Benefits Food Producing and Companion Animals
Purdue University's School of Veterinary
Medicine is involved in research aimed at
reducing the cost and number of animals
needed to perform disease research. Our
laboratory is conducting in vitro disease
modeling to benefit food producing and
companion animals. The in vitro disease
modeling studies are primarily concerned
with cell/organ growth and how they are
affected by various disease processes.
Fundamental understanding of various
interactions, using target cells, will assist
in treating and preventing disease processes in the total animal.   Cooperative
studies are being done with Drs. Bottoms,
Fessler, and Turek to study the inhibitory
effect of bacterial endotoxin on equine
and bovine endothelial cells. They have
demonstrated In vivo that damage to the
endothelial cells lining the major blood
vessels is extensive and may be responsible for irreversible changes that occur
during endotoxic shock. Understanding
this fundamental disease mechanism
should aid in the development of preventive and therapeutic measures to control
endotoxic shock in horses and cattle and
assist in studying this disease in man.
Musculoskeletal diseases account for significant financial losses to the food producing industries. Drs. Van Sickle and
Kincaid have studied arthritic associated
diseases of dogs and pigs in vivo. In collaboration with these investigators, porcine
articular chondrocytes are being evaluated in vitro. Cell cultures have demonstrated two types of chondrocytes with
different growth rates. The growth rate
differences and the interactions of these
cells in the growing pig are being studied
to assist in understanding lameness.
Controlling cellular growth and metabolic
processes are primary objectives of the
in vitro disease modeling laboratory. Cooperative studies with  members of the
Dr. Lamar and Gail Sudlow conferring on
the status of an endothelial cell culture.
Dispersed cell cultures of bovine (A) and equine (B) endothelial cells being prepared
for an endotoxin assay by Dr. Bottoms' laboratory.
Purdue Comparative Oncology Program     This information will be used to identify
are being conducted. Primary cell cultures established from canine lymphosarcomas and mast cell tumors are morpho-
Scanning electron photomicrograph of a porcine articular chondrocyte In culture, logically characterized using phase con-
3000 X. ^jrast and electron microscope techniques.
changes that may be helpful in developing
a method to predict renewed growth of
the tumor following therapy.
Carlton H. Lamar, ^LM., Ph.D.