Extension Mimeo AS, no. 358 (Jan. 1967) |
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Stilbestrol for Cattle K. G. MacDonald, D. R. Zimmerman, and L L. Wilson, Animal Sciences Department AS-358 Jan. 1967 Introduction For more than 30 years, the importance of natural hormones that are secreted by the body has been recognized. In 1937 two British chemists, Dodds and Lawson, first synthesized diethylstilbestrol. The use of stilbestrol in beef cattle rations is one of the most significant developments in beef cattle feeding. The primary effects of its use which are increased rate of gain and improved feed efficiency, have been of benefit to many cattle feeders. Stilbestrol has often made the difference between profit and loss for cattle feeding operations. What is diethylstilbestrol? steers, heifers and bulls. The experimental levels of implanted stilbestrol have ranged from 6 to 120 milligrams, with the most satisfactory results obtained with 24 to 36 milligrams. Daily oral treatment of 10 milligrams per animal has compared favorably with implantation. Most experiments showed that stilbestrol produced both growth effects and estrogenic effects. The growth effects manifested themselves in increased rate of gain and improved feed efficiency. The estrogenic effects are raised tailheads, depressed loins, mammary development, swelling of the vulva, and on occasion prolapses of the vagina or uterus. In all the trials conducted to date, stilbestrol produces some estrogenic effects, in addition to growth response. Diethylstilbestrol (DES) does not occur in nature. It is a synthetic chemical compound having many of the effects of natural female sex hormones which are secreted by the ovary. Stilbestrol has an advantage because it is effective in animals no matter whether administered in the feed, implanted as a solid pellet beneath the skin, or injected in solution The first trials showing the growth stimulating effects of diethylstilbestrol in beef cattle were conducted at Purdue University in 1947 with Hereford heifers implanted with 42 milligrams of stilbestrol. Since this early work, many trials have been conducted to study the effects of female hormones in The most serious of these estrogenic effects is the vaginal or uterine prolapse, which may force the feeder to sell the animal before she is finished, or in the very serious cases may result in the loss of the heifer. The extent to which heifers show estrogenic effects is influenced by many factors. Two of the most important factors are (1) the amount of hormone present in the blood stream of the individual animal and (2) the reaction of each heifer to the hormone. Implantation of stilbestrol This technique involves implanting small pellets of stilbestrol in the loose skin near Beef Section • Animal Sciences Department Cooperative Extension Service, PURDUE UNIVERSITY, Lafayette, Indiana Beef Nutrition
Object Description
Title | Extension Mimeo AS, no. 358 (Jan. 1967) |
Purdue Identification Number | UA-14-13-mimeoas358 |
Title of Issue | Stilbestrol for Cattle |
Author of Issue |
MacDonald, K. G. (Kenneth G.) Zimmerman, Dwane R. Wilson, Lowell L. |
Date of Original | 1967 |
Publisher | Purdue University. Cooperative Extension Service |
Subjects (LCSH) |
Diethylstilbestrol Hormones in animal nutrition Beef cattle--Growth |
Genre | Periodical |
Collection Title | Extension Mimeo AS (Purdue University. Agricultural Extension Service) |
Rights Statement | Copyright Purdue University. All rights reserved. |
Coverage | United States - Indiana |
Type | text |
Format | JP2 |
Language | Eng |
Repository | Purdue University Libraries |
Date Digitized | 06/10/2015 |
Digitization Information | Original scanned at 400 ppi on a BookEye 3 scanner using Opus software. Display images generated in Contentdm as JP2000s; file format for archival copy is uncompressed TIF format. |
URI | UA-14-13-mimeoas358.tif |
Description
Title | Extension Mimeo AS, no. 358 (Jan. 1967) |
Purdue Identification Number | UA-14-13-mimeoas358 |
Title of Issue | Stilbestrol for Cattle |
Author of Issue |
MacDonald, K. G. (Kenneth G.) Zimmerman, Dwane R. Wilson, Lowell L. |
Date of Original | 1967 |
Publisher | Purdue University. Cooperative Extension Service |
Subjects (LCSH) |
Diethylstilbestrol Hormones in animal nutrition Beef cattle--Growth |
Genre | Periodical |
Collection Title | Extension Mimeo AS (Purdue University. Agricultural Extension Service) |
Rights Statement | Copyright Purdue University. All rights reserved. |
Coverage | United States - Indiana |
Type | text |
Format | JP2 |
Language | Eng |
Transcript | Stilbestrol for Cattle K. G. MacDonald, D. R. Zimmerman, and L L. Wilson, Animal Sciences Department AS-358 Jan. 1967 Introduction For more than 30 years, the importance of natural hormones that are secreted by the body has been recognized. In 1937 two British chemists, Dodds and Lawson, first synthesized diethylstilbestrol. The use of stilbestrol in beef cattle rations is one of the most significant developments in beef cattle feeding. The primary effects of its use which are increased rate of gain and improved feed efficiency, have been of benefit to many cattle feeders. Stilbestrol has often made the difference between profit and loss for cattle feeding operations. What is diethylstilbestrol? steers, heifers and bulls. The experimental levels of implanted stilbestrol have ranged from 6 to 120 milligrams, with the most satisfactory results obtained with 24 to 36 milligrams. Daily oral treatment of 10 milligrams per animal has compared favorably with implantation. Most experiments showed that stilbestrol produced both growth effects and estrogenic effects. The growth effects manifested themselves in increased rate of gain and improved feed efficiency. The estrogenic effects are raised tailheads, depressed loins, mammary development, swelling of the vulva, and on occasion prolapses of the vagina or uterus. In all the trials conducted to date, stilbestrol produces some estrogenic effects, in addition to growth response. Diethylstilbestrol (DES) does not occur in nature. It is a synthetic chemical compound having many of the effects of natural female sex hormones which are secreted by the ovary. Stilbestrol has an advantage because it is effective in animals no matter whether administered in the feed, implanted as a solid pellet beneath the skin, or injected in solution The first trials showing the growth stimulating effects of diethylstilbestrol in beef cattle were conducted at Purdue University in 1947 with Hereford heifers implanted with 42 milligrams of stilbestrol. Since this early work, many trials have been conducted to study the effects of female hormones in The most serious of these estrogenic effects is the vaginal or uterine prolapse, which may force the feeder to sell the animal before she is finished, or in the very serious cases may result in the loss of the heifer. The extent to which heifers show estrogenic effects is influenced by many factors. Two of the most important factors are (1) the amount of hormone present in the blood stream of the individual animal and (2) the reaction of each heifer to the hormone. Implantation of stilbestrol This technique involves implanting small pellets of stilbestrol in the loose skin near Beef Section • Animal Sciences Department Cooperative Extension Service, PURDUE UNIVERSITY, Lafayette, Indiana Beef Nutrition |
Repository | United States - Indiana |
Date Digitized | 06/10/2015 |
Digitization Information | Original scanned at 400 ppi on a BookEye 3 scanner using Opus software. Display images generated in Contentdm as JP2000s; file format for archival copy is uncompressed TIF format. |
URI | UA-14-13-mimeoas358.tif |
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